Tests in rats showed the dye, called brilliant blue G, a close relative of the common food dye Blue no. 1, crossed into the spinal fluid and helped block inflammation, Maiken Nedergaard of the University of Rochester Medical Center and colleagues reported.
"We have no effective treatment now for patients who have an acute spinal cord injury," Dr. Steven Goldman, who worked on the study, said in a statement.
"Our hope is that this work will lead to a practical, safe agent that can be given to patients shortly after injury, for the purpose of decreasing the secondary damage that we have to otherwise expect."
When nerve cells in the brain or spine are damaged, they often release a spurt of chemicals that causes nearby cells to die. No one is sure why, and stopping this process is key to preventing the damage that continues to build after a stroke or spinal cord injury.
One of the chemicals is ATP. Nedergaard's team looked for something that would interfere with this and found the blue dye, which they called BBG, would do this via the P2X7R receptor or doorway.
http://www.msnbc.msn.com/id/32178712/ns/health-more_health_news/


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